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Analysis of Health Outcomes in Vaccinated and Unvaccinated Children: Developmental Delays, Asthma, Ear Infections and Gastrointestinal Disorders

Analysis of Health Outcomes in Vaccinated and Unvaccinated Children: Developmental Delays, Asthma, Ear Infections and Gastrointestinal Disorders
Analysis of Health Outcomes in Vaccinated and Unvaccinated Children: Developmental Delays, Asthma, Ear Infections and Gastrointestinal Disorders

“Going Natural” in First Year of Life Resulted in Better Health Outcomes

On October 20, 2022, the Advisory Committee on Immunization Practices (ACIP) voted unanimously to include mRNA COVID-19 vaccines on the list of routine immunizations for adults and children 6 months and older. This sent young mothers and fathers into a panic since previously ACIP had been trusted as an advisor to pediatricians. Parents knew babies were not a risk for serious COVID-19 outcomes. They were concerned the vaccines were genetic, long-lasting, produced the harmful Wuhan Spike protein, and had no long-term safety testing. If the shots were given on schedule every six months it meant a massive exposure to a brand new genetic biotechnology. This development has prompted so many parents to ask me about the necessity and the safety of the entire ACIP routine schedule. Conversely, they want to know: is it OK to go “natural” in the first year of life with no vaccines taken?

Hooker and Miller examined data from three medical practices in the United States with children born between November 2005 and June 2015, vaccinated children were compared to unvaccinated children during the first year of life for later incidence of developmental delays, asthma, ear infections and gastrointestinal disorders. Subjects were a minimum of 3 years of age, stratified based on medical practice, year of birth and gender and compared using a logistic regression model. Vaccination before 1 year of age was associated with increased odds of developmental delays (OR = 2.18, 95% CI 1.47–3.24), asthma (OR = 4.49, 95% CI 2.04–9.88) and ear infections (OR = 2.13, 95% CI 1.63–2.78). A quartile analysis of the number of shots was performed to examine dose-response relationships. Higher odds ratios were observed in Quartiles 3 and 4 (where more vaccine doses were received) for all four health conditions considered, as compared to Quartile 1.

Hooker BS, Miller NZ. Analysis of health outcomes in vaccinated and unvaccinated children: Developmental delays, asthma, ear infections and gastrointestinal disorders. SAGE Open Med. 2020 May 27;8:2050312120925344. doi: 10.1177/2050312120925344. PMID: 32537156; PMCID: PMC7268563.

Since these data are not randomized, there may be sources of selection bias and confounding that could play a role in the results reported. However, it is clear no matter what the explanation, unvaccinated children in the first year of life are much healthier when they arrive at the three-year milestone as compared to vaccinated.

These data point to the need for a complete re-examination of the ACIP childhood vaccine schedule. Medical necessity, clinical indication, risk stratification, timing, safety and efficacy should all be reconsidered. If ACIP had not recommended the COVID-19 vaccines for babies, we may not have seen this large shift in parental sentiment on childhood vaccinations.

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