An initial look at lipid nanoparticles around the body.
Lipid nanoparticles (LNPs) are used to deliver fragile mRNA strands into cells. They are tiny balls of fat which protect the mRNA from being destroyed and allow it to enter cells undetected. Toxicity of LNPs has always been a concern but I am not expert enough to comment on whether they are or are not toxic in the Pfizer vaccine.
From early on in the vaccination programme, fact-checkers (https://www.ucsf.edu/news/2021/01/419691/covid-19-vaccine-fact-vs-fiction-expert-weighs-common-fears) assured us that mRNA “is likely to stay right in the arm where it’s injected and get taken up by the cells there.” We know this is not correct and these latest documents confirm that.
This document – a Nonclinical Overview (https://phmpt.org/wp-content/uploads/2022/03/125742_S1_M2_24_nonclinical-overview.pdf) and this Pharmacokinetics Written Summary
https://phmpt.org/wp-content/uploads/2022/03/125742_S1_M2_26_pharmkin-written-summary.pdf Looked at the distribution of LNPs in the blood, plasma and selected tissues of Wistar Han rats, over 48 hours after a single injection. The full results can be seen here
As you can see, the LNPs were present in all the organs tested. As would be expected, the injection site had the highest levels which started declining after 4 hours. At 48 hours the highest concentration of LNPs were at the injection site and represented almost 25% of the administered dose.
However, there were high concentrations of LNPs in other organs, just not as high as at the injection site. The next highest was in the liver with over 16% of the administered dose in that organ at 48 hours. High concentrations were also seen in adrenal glands, spleen, bone marrow and ovaries.
What is concerning about this is that by 48 hours the concentration of LNPs was falling in the injection site but still rising in the other organs listed above. It was also still rising in many other organs where the concentration was much lower.
What happened after 48 hours? How much did the concentration of LNPs rise in the other organs and for how long? Why did the study finish at 48 hours or not get extended after it was obvious the levels were still climbing?